Obesity / Weight Loss

A very low calorie ketogenic diet improves weight loss and quality of life in patients with adjustable gastric banding.

Taus M , Fumelli D , Busni D , Borroni F , Sebastianelli S , Nicolai G , Nicolai A

Non-randomized 2 arm prospective with 20 participants.  KD can improve the weight loss and quality of life in patients who underwent LAGB and failed at losing more weight allowing a weight loss comparable to that obtained with a further calibration and it is useful to to avoid drastic calibrations and their collateral effects

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Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very lowcarbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes

Laura R. Saslow, Jennifer J. Daubenmier, Judith T. Moskowitz, Sarah Kim, Elizabeth J. Murphy, Stephen D. Phinney, Robert Ploutz-Snyder, Veronica Goldman, Rachel M. Cox, Ashley E. Mason, Patricia Moran & Frederick M. Hecht

RCT with 34 particpants.  The results suggest that adults with prediabetes or noninsulin-dependent type 2 diabetes may be able to improve glycemic control with less medication by following an ad libitum very low-carbohydrate ketogenic diet compared to a moderate-carbohydrate, calorie-restricted low-fat diet. Additional research should examine both clinical outcomes and adherence beyond 12 months.

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A Novel Intervention Including Individualized Nutritional Recommendations Reduces Hemoglobin A1c Level, Medication Use, and Weight in Type 2 Diabetes

Amy L McKenzie, PhD ; Sarah J Hallberg, DO, MS ; Brent C Creighton, PhD ; Brittanie M Volk, RD, PhD ; Theresa M Link, RD, CDE ; Marcy K Abner, RD ; Roberta M Glon, RN, BSN ; James P McCarter, MD, PhD ; Jeff S Volek, RD, PhD ; Stephen D Phinney, MD, PhD

This study, non-randomized parallel arm prospective with 262 participants, demonstrates an individualized program delivered and supported remotely that incorporates nutritional ketosis can be highly effective in improving glycemic control and weight loss in adults with T2D while significantly decreasing medication use.

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Long-term effects of a ketogenic diet in obese patients

Hussein M Dashti, MD PhD FICS FACS, Thazhumpal C Mathew, MSc PhD FRCPath, Talib Hussein, MB ChB, Sami K Asfar, MB ChB MD FRCSEd FACS, Abdulla Behbahani, MB ChB FRCS FACSI PhD FICS FACS, Mousa A Khoursheed, MB ChB FRCS FICS, Hilal M Al-Sayer, MD PhD FICS FACS, Yousef Y Bo-Abbas, MD FRCPC, and Naji S Al-Zaid, BSc PhD

To determine the effects of a 24-week ketogenic diet (consisting of 30 g carbohydrate, 1 g/kg body weight protein, 20% saturated fat, and 80% polyunsaturated and monounsaturated fat) in obese patients.

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