Marina M. Pearsall, MD, PhD; Gurney F Pearsall Jr, MD
Scientists from Gladstones Institutes have unearthed a specific compound that acts as “the body’s major source of energy during exercise or fasting,” says senior investigator Dr. Eric Verdin. This mechanism, known as β-hydroxybutyrate, works by blocking a chemical process that increases oxidative stress on the body’s cells.
A novel mechanism by which a type of low-carb, low-calorie diet — called a “ketogenic diet” — could delay the effects of aging has been identified by the researchers.
Peter Attia, MD
For reasons I’m still struggling to understand, the idea of “nutritional ketosis” (NK, to be distinguished from starvation ketosis, SK or diabetic ketoacidosis, DKA) is often discussed and debated in much the same way as religion or politics. Perhaps this can be said of all nutrition, which is a shame. Nevertheless, in my continued defiance of such sensitive topics, I’d like to add another layer of complexity and nuance to this discussion.
John Erdman, Maria Oria, and Laura Pillsbury, Editors: Institute of Medicine Of The National Academies
The ketogenic diet is composed of 80–90 percent fat and provides adequate protein but limited carbohydrates (Gasior et al., 2006). In normal metabolism, carbohydrates contained in food are converted into glucose, but in the presence of carbohydrate restriction, fatty acid oxidation becomes favored, and the liver converts fat into fatty acids and ketone bodies that serve as an efficient alternative fuel for brain cells.
In 1993, 11 month old Charlie Abrahams developed difficult to control epilepsy. As a last resort, while Charlie was experiencing multiple daily seizures and multiple daily medications, his parents turned to a Ketogenic Diet for help. The diet worked. Charlie became seizure and drug free within a month. He was on the diet for five years and now eats whatever he wants. He has never had another seizure.
Last year I started a nutritional self experiment. Almost half a year later I think it’s time to share my experiences. Admittedly, I’m going on a bit of a tangent here compared to what I usually want to write about. But this journey still has its roots in something which is not so unrelated.
Kris Gunnars, BSc
Low-carb diets have been controversial for decades. They were originally demonized by fat-phobic health professionals and the media. People believed that these diets would raise cholesterol and cause heart disease because of the high fat content. However… times are changing.
Prof. Tim Noakes
It’s taken a lifetime to realise it but Professor Tim Noakes now believes the over consumption of refined carbohydrates may be toxic for the body.